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Pharmaleads has designed high performance chemical tools for the caracterisation of proteases (or peptidases), and more specifically a library of substrates with repressed fluorescence that allow for the very high sensitivity detection of any family of proteases.
This library has been tested on most of the known zinc metallopeptidases and has lead to new substrates for these enzymes (NEP, NEPII, ACE, ECE, Matrixine, etc.).
Such new substrates combined with the PHARMALEADS high performance fluorophore agent are the product of choice to perform HTS and to allow the discovery of efficient inhibitors or activators.
To further address your specific needs in protease research, PHARMALEADS provides custom synthesis and assay development for proteases of interest.
To know more about our high value services, please contact us.
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